1. Bora Baysal - NeoGenomics Laboratories
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Dr. Baysal joined NeoGenomics as a Senior Hematopathologist in 2022. Before joining NeoGenomics, Dr. Baysal served as an Associate Professor of Oncology and a Staff Physician (Hematopathology) in the Department of Pathology and Laboratory Medicine at Roswell Park Cancer Institute in Buffalo, NY. Dr. Baysal is the recipient of many research grants including a NIH-funded research grant related to the seminal discovery of a human mitochondrial cancer gene as well as a grant from the Roswell Park Alliance Foundation leading to the discovery of new RNA editing enzymes in immune cells. Dr.
2. [PDF] Looking Back, Moving Forward - Pitt Public Health
Nov 6, 2023 · I also want to strengthen our emphasis on diversity, equity and inclusion. To me, this goes beyond race and ethnicity to include LGBTQIA ...
3. TNF-α and its soluble receptors mediate the relationship between ...
Apr 6, 2020 · TNF-α and its soluble receptors mediate the relationship between prior severe mood episodes and cognitive dysfunction in euthymic bipolar disorder.
Bipolar disorder (BD) is one of the most disabling mental health conditions in the world. Symptoms of cognitive impairment in BD contribute directly to occupational and social deficiencies and are very difficult to treat. Converging evidence suggests ...
4. [PDF] Roswell Park Cancer Institute (RPCI) and Jamestow
Bora Baysal, MD, PhD, Associate Professor of Oncology in the Department of Pathology and. Laboratory Medicine, received $50,000 for his project, “Structural ...
5. [PDF] PITTMED - Pitt Med Magazine - University of Pittsburgh
Bora Baysal and Bernard Devlin, assistant professors of psychiatry, have linked for the first time flaws that alter mitochondria to genetically inherited ...
6. COVID-19 challenges: From SARS-CoV-2 infection to effective ...
Sep 9, 2021 · Aspects of SARS-CoV-2 infection lika pathogenicity, host's immune response, ethnicity, viral mutation rate, rapid variant appearance and ...
In January 2020, the World Health Organization (WHO) identified a new zoonotic virus, SARS-CoV-2, responsible for causing the COVID-19 (coronavirus disease 2019). Since then, there has been a collaborative trend between the scientific community and industry. ...
7. 2017 RNA Editing Conference GRC
Bora Baysal (Roswell Park Cancer Institute, USA). "APOBEC3 Enzymes and the Expanding Role C to U RNA Editing in Human Transcriptome Diversity". 8:05 pm - 8:10 ...
The 2017 Gordon Research Conference on RNA Editing will be held in Ventura, California. Apply today to reserve your spot.
8. High Mitochondrial DNA Stability in B-Cell Chronic Lymphocytic ... - PLOS
Our results suggest that mtDNA instability is not the primary causal factor in B-CLL. A secondary role of mtDNA mutations cannot be fully ruled out.
Background Chronic Lymphocytic Leukemia (CLL) leads to progressive accumulation of lymphocytes in the blood, bone marrow, and lymphatic tissues. Previous findings have suggested that the mtDNA could play an important role in CLL. Methodology/Principal Findings The mitochondrial DNA (mtDNA) control-region was analyzed in lymphocyte cell DNA extracts and compared with their granulocyte counterpart extract of 146 patients suffering from B-Cell CLL; B-CLL (all recruited from the Basque country). Major efforts were undertaken to rule out methodological artefacts that would render a high false positive rate for mtDNA instabilities and thus lead to erroneous interpretation of sequence instabilities. Only twenty instabilities were finally confirmed, most of them affecting the homopolymeric stretch located in the second hypervariable segment (HVS-II) around position 310, which is well known to constitute an extreme mutational hotspot of length polymorphism, as these mutations are frequently observed in the general human population. A critical revision of the findings in previous studies indicates a lack of proper methodological standards, which eventually led to an overinterpretation of the role of the mtDNA in CLL tumorigenesis. Conclusions/Significance Our results suggest that mtDNA instability is not the primary causal factor in B-CLL. A secondary role of mtDNA mutations cannot be fully ruled out under the hypothesis that the progressive accumulation of mtDNA instabilities could...